Rosmarinic Acid–Human Pharmacokinetics and Health Benefits

BIOACTIVITY AND POTENTIAL HEALTH BENEFITS OF ROSMARINIC ACID Minireview

Substantial attention has been given to primary cancer prevention in daily life. Secondary metabolites of plants in the form of functional foods or nutraceuticals are known as preventive agents for a variety of diseases, including cancer. Rosmarinic acid (RA) is a naturally occurring polyphenolic compound, which contributes to the beneficial and health-promoting effects of herbs, spices and med...

Fasting: Benefits and probable health harmfulness from the Islamic perspective

Fasting is a form of Islamic worship to approach God.  There is a direct relationship between fasting, abstaining from eating and drinking, and an individual’s health as well as his ill-health. Therefore, it is of utmost importance in the Islamic perspective to weigh the spiritual benefits achieved through fasting against its probable harmfulness to an individual’s health. Regarding fasting, th...

Pharmacokinetics of rosmarinic acid in rats by LC-MS/MS: absolute bioavailability and dose proportionality

Rosmarinic acid (RA), one of the main bioactive compounds of Rosmarinus officinalis L., exhibits diverse pharmacological effects. However, its oral absolute bioavailability and dose proportionality in vivo have not been comprehensively studied. In the present study, a validated LC-MS/MS method was developed for the determination of RA in rat plasma. Pharmacokinetic parameters were obtained foll...

Health Benefits of Islamic Intermittent Fasting

Background & Objective:  Islamic fasting is observed by millions of Muslims across the world during the holy month of Ramadan and other specific  days of the lunar year. Fasting  Muslims  abstain from eating and drinking from dawn until sunset. Depending on season and geographical location, Muslims  maintain fasting for approximately 13-18 hours per day. The present study aimed to review the be...

Cycling: Health Benefits and Risks